SFC Columns

SFC Columns

Alcyon SFC

    YMC columns for SFC

    YMC offers chiral and achiral phases for supercritical fluid chromatography (SFC) applications to provide the chemist with a number of options for SFC separations.

    SFC can offer some advantages over HPLC for similar applications. The low viscosity of supercritical carbon dioxide allows for analytical separations 3-5 times faster than those for normal phase HPLC. Speed of the SFC separations, conservation of organic solvents, and more concentrated product fractions make SFC a desirable preparative chromatographic technique for purifying chemical mixtures.

    All YMC SFC columns are specifically packed in a SFC compatible hardware and are tested under SFC conditions.

     

    Alcyon SFC columns are characterised by:

    • 10 chiral/achiral phases (+ 4 additional phases)
    • hardware especially dedicated to SFC use
    • analytical or preparative scale application
    • YMC's hallmark attention to particle and chemistry specifications and quality
    • column certificate in SFC mode
    Application Columns Compound name
    Acidic non-steroidal anti-inflammatory drugs Alcyon SFC SIL Ibuprofen Fenoprofen Naproxen Ketoprofen Sulindac
    Analgesics Alcyon SFC SIL Apronalide Bromovalerylurea Ibuprofen Caffeine Acetylsalicylic acid Acetaminophen Indomethacin
    Androgens Alcyon SFC Triart PFP Androsterone Dehydroisoandrosterone Testosterone Fluoxymesterone
    Antiepileptics Alcyon SFC SIL Phenytoin Carbamazepine Primidone
    Betablocker Alcyon SFC Triart Diol Timolol Metoprolol Propranolol Acebutolol Pindolol Atenolol Carvedilol
    Donepezil Alcyon SFC CSP Cellulose-C Donepezil
    Ingredients in a cough/cold medication Alcyon SFC Triart PFP Ibuprofen Acetaminophen Caffeine Dextromethorphan
    N-CBZ-DL-Alanine Alcyon SFC CSP Amylose-C N-CBZ-DL-Alanine
    Naringenin Alcyon SFC CSP Cellulose-SB Naringenin
    Polyaromatic hydrocarbons Alcyon SFC Triart C18 Naphthalene Biphenyl Acenaphthene o-Terphenyl Anthracene m-Terphenyl p-Terphenyl Triphenylene
    Propranolol Alcyon SFC CSP Cellulose-C Propranolol
    Purine alkaloids Alcyon SFC Triart Diol Trigonelline hydrochloride Phenol Caffeine Theophylline Theobromine
    Steroids Alcyon SFC Triart Diol Progesterone Corticosterone Deoxycorticosterone Hydrocortisone
    Specifications Alcyon Chiral/Achiral
     
    Alcyon SFC CSP
    Amylose-C
    Alcyon SFC CSP
    Cellulose-C
    Alcyon SFC CSP
    Amylose-SA
    Alcyon SFC CSP
    Cellulose-SB
    Alcyon SFC CSP
    Cellulose-SC
    Type coated immobilised
    Chiral selector Amylose tris (3,5-dimethyl-phenylcarbamate Cellulose tris (3,5-dimethyl-phenylcarbamate Amylose tris (3,5-dimethyl-phenylcarbamate Cellulose tris (3,5-dimethyl-phenylcarbamate Cellulose tris (3,5-dichloro-phenylcarbamate
    USP L51 L40 - - -
    Particle Size 3, 5 µm
    pH Range 3.5 - 6.5 2.0 - 9.0
    Shipping Solvent 2-propanol
    Pressure Limit
    Inner diameter of 2.1 / 3.0 / 4.6 mm: 300 bar
    Inner diameter of 10 / 20 mm: 200 bar

     

     
    Alcyon SFC
    Triart C18
    Alcyon SFC
    Triart Diol
    Alcyon SFC
    Triart PFP
    Alcyon SFC
    CN
    Alcyon SFC
    SIL
    Modification C18 1,2-Dihydroxypropyl
    Pentafluorophenylpropyl
    Cyanopropyl Silica
    USP L1 L20 L43 L10 L3
    Particle Size 5 µm
    Pore Size 12 nm / 120 Å
    pH Range 1.0 - 12.0 2.0 - 10.0 1.0 - 8.0 2.0 - 7.5 2.0 - 7.5
    Shipping Solvent 2-propanol
    Pressure Limit
    Inner diameter of 2.1 / 4.6 mm: 300 bar
    Inner diameter of 10 / 20 mm: 200 bar

     

    Specifications Additional Phases
     
    YMC-Pack
    2-Ethyl pyridine*
    YMC-Pack
    Diethylaminopropyl*
    YMC-Pack
    Propyl acetamide*
    YMC-Pack
    Pyridine amide*
    Particle Size 5 µm (3 and 10 µm on request)
    Pore Size 6 nm / 60 Å
    Shipping Solvent 2-propanol
    Pressure Limit 250 bar

    *not in Alcyon Hardware, but in so called "PS" type hardware also exclusively dedicated to SFC use

    Title Document Type Language Phase Type Download
    Rapid SFC Analysis of Vitamin D3 and Related Compounds with Alcyon SFC Triart-Diol Application Note E
    Alcyon SFC Columns Brochure E
    Alcyon SFC Amloyse-SA, Cellulose-SB, Cellulose-SC Care and Use Care and Use Instructions E
    Alcyon SFC Amylose-C, Cellulose-C Care and Use Care and Use Instructions E
    Alcyon SFC Triart Diol, C18, PFP, SIL, CN Care and Use Care and Use Instructions E
    Fast Method Screening for Separation of Enantiomers in HPLC and SFC Utilizing Novel Polysaccharide Type Chiral Stationary Phase Poster E Please login
    SFC Analytical Method Development for Vitamin D3 and Related Compounds Poster E Please login
    Toward Development of “Generic” Separation Methods for Achiral Pharmaceutical Analysis Using SFC Poster E Please login
    Analyse von biologisch aktiven Verbindungen mit CHIRAL ART Amylose-SA im SFC-Modus Product Information D Please login
    Analysis of biologically active compounds using CHIRAL ART Amylose-SA in SFC mode Product Information E Please login

    Please login to see the prices (if needed insert link to login page).

    Product Description Price (EUR) Stock
    CN12S05-1546WTS Alcyon SFC CN, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 150 x 4.6 mm -
    CN12S05-15Q1WTS Alcyon SFC CN, Narrowbore SFC Column (2.1 mm i.d.), 12 nm, S-5 µm, 150 x 2.1 mm -
    CN12S05-2510WTS Alcyon SFC CN, semi-preparative SFC column (10 mm i.d.), 12 nm, S-5 µm, 250 x 10.0 mm -
    CN12S05-2520WTS Alcyon SFC CN, semi-preparative SFC column (20 mm i.d.), 12 nm, S-5 µm, 250 x 20.0 mm -
    CN12S05-2546WTS Alcyon SFC CN, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 250 x 4.6 mm -
    KAN99S03-0503WTS Alcyon SFC CSP Amylose-C, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 50 x 3.0 mm -
    KAN99S03-1003WTS Alcyon SFC CSP Amylose-C, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 100 x 3.0 mm -
    KAN99S03-1503WTS Alcyon SFC CSP Amylose-C, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 150 x 3.0 mm -
    KAN99S03-1546WTS Alcyon SFC CSP Amylose-C, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 150 x 4.6 mm -
    KAN99S03-15Q1WTS Alcyon SFC CSP Amylose-C, Classical Analytical SFC Column (2.1 mm i.d.), S-3 µm, 150 x 2.1 mm -
    KAN99S03-2546WTS Alcyon SFC CSP Amylose-C, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 250 x 4.6 mm -
    KAN99S05-1546WTS Alcyon SFC CSP Amylose-C, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 150 x 4.6 mm -
    KAN99S05-15Q1WTS Alcyon SFC CSP Amylose-C, Narrowbore SFC Column (2.1 mm i.d.), S-5 µm, 150 x 2.1 mm -
    KAN99S05-2510WTS Alcyon SFC CSP Amylose-C, semi-preparative SFC column (10.0 mm i.d.), S-5 µm, 250 x 10.0 mm -
    KAN99S05-2520WTS Alcyon SFC CSP Amylose-C, semi-preparative SFC column (20.0 mm i.d.), S-5 µm, 250 x 20.0 mm -
    KAN99S05-2546WTS Alcyon SFC CSP Amylose-C, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 250 x 4.6 mm -
    KCN99S03-0503WTS Alcyon SFC CSP Cellulose-C, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 50 x 3.0 mm -
    KCN99S03-1003WTS Alcyon SFC CSP Cellulose-C, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 100 x 3.0 mm -
    KCN99S03-1503WTS Alcyon SFC CSP Cellulose-C, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 150 x 3.0 mm -
    KCN99S03-1546WTS Alcyon SFC CSP Cellulose-C, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 150 x 4.6 mm -
    KCN99S03-15Q1WTS Alcyon SFC CSP Cellulose-C, Classical Analytical SFC Column (2.1 mm i.d.), S-3 µm, 150 x 2.1 mm -
    KCN99S03-2546WTS Alcyon SFC CSP Cellulose-C, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 250 x 4.6 mm -
    KCN99S05-1546WTS Alcyon SFC CSP Cellulose-C, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 150 x 4.6 mm -
    KCN99S05-15Q1WTS Alcyon SFC CSP Cellulose-C, Narrowbore SFC Column (2.1 mm i.d.), S-5 µm, 150 x 2.1 mm -
    KCN99S05-2510WTS Alcyon SFC CSP Cellulose-C, semi-preparative SFC column (10.0 mm i.d.), S-5 µm, 250 x 10.0 mm -
    KCN99S05-2520WTS Alcyon SFC CSP Cellulose-C, semi-preparative SFC column (20.0 mm i.d.), S-5 µm, 250 x 20.0 mm -
    KCN99S05-2546WTS Alcyon SFC CSP Cellulose-C, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 250 x 4.6 mm -
    KSA99S03-0503WTS Alcyon SFC CSP Amylose-SA, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 50 x 3.0 mm -
    KSA99S03-1003WTS Alcyon SFC CSP Amylose-SA, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 100 x 3.0 mm -
    KSA99S03-1503WTS Alcyon SFC CSP Amylose-SA, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 150 x 3.0 mm -
    KSA99S03-1546WTS Alcyon SFC CSP Amylose-SA, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 150 x 4.6 mm -
    KSA99S03-15Q1WTS Alcyon SFC CSP Amylose-SA, Classical Analytical SFC Column (2.1 mm i.d.), S-3 µm, 150 x 2.1 mm -
    KSA99S03-2546WTS Alcyon SFC CSP Amylose-SA, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 250 x 4.6 mm -
    KSA99S05-1546WTS Alcyon SFC CSP Amylose-SA, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 150 x 4.6 mm -
    KSA99S05-15Q1WTS Alcyon SFC CSP Amylose-SA, Narrowbore SFC Column (2.1 mm i.d.), S-5 µm, 150 x 2.1 mm -
    KSA99S05-2510WTS Alcyon SFC CSP Amylose-SA, semi-preparative SFC column (10.0 mm i.d.), S-5 µm, 250 x 10.0 mm -
    KSA99S05-2520WTS Alcyon SFC CSP Amylose-SA, semi-preparative SFC column (20.0 mm i.d.), S-5 µm, 250 x 20.0 mm -
    KSA99S05-2546WTS Alcyon SFC CSP Amylose-SA, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 250 x 4.6 mm -
    KSB99S03-0503WTS Alcyon SFC CSP Cellulose-SB, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 50 x 3.0 mm -
    KSB99S03-1003WTS Alcyon SFC CSP Cellulose-SB, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 100 x 3.0 mm -
    KSB99S03-1503WTS Alcyon SFC CSP Cellulose-SB, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 150 x 3.0 mm -
    KSB99S03-1546WTS Alcyon SFC CSP Cellulose-SB, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 150 x 4.6 mm -
    KSB99S03-15Q1WTS Alcyon SFC CSP Cellulose-SB, Classical Analytical SFC Column (2.1 mm i.d.), S-3 µm, 150 x 2.1 mm -
    KSB99S03-2546WTS Alcyon SFC CSP Cellulose-SB, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 250 x 4.6 mm -
    KSB99S05-1546WTS Alcyon SFC CSP Cellulose-SB, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 150 x 4.6 mm -
    KSB99S05-15Q1WTS Alcyon SFC CSP Cellulose-SB, Narrowbore SFC Column (2.1 mm i.d.), S-5 µm, 150 x 2.1 mm -
    KSB99S05-2510WTS Alcyon SFC CSP Cellulose-SB, semi-preparative SFC column (10.0 mm i.d.), S-5 µm, 250 x 10.0 mm -
    KSB99S05-2520WTS Alcyon SFC CSP Cellulose-SB, semi-preparative SFC column (20.0 mm i.d.), S-5 µm, 250 x 20.0 mm -
    KSB99S05-2546WTS Alcyon SFC CSP Cellulose-SB, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 250 x 4.6 mm -
    KSC99S03-0503WTS Alcyon SFC CSP Cellulose-SC, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 50 x 3.0 mm -
    KSC99S03-1003WTS Alcyon SFC CSP Cellulose-SC, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 100 x 3.0 mm -
    KSC99S03-1503WTS Alcyon SFC CSP Cellulose-SC, Classical Analytical SFC Column (3.0 mm i.d.), S-3 µm, 150 x 3.0 mm -
    KSC99S03-1546WTS Alcyon SFC CSP Cellulose-SC, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 150 x 4.6 mm -
    KSC99S03-15Q1WTS Alcyon SFC CSP Cellulose-SC, Classical Analytical SFC Column (2.1 mm i.d.), S-3 µm, 150 x 2.1 mm -
    KSC99S03-2546WTS Alcyon SFC CSP Cellulose-SC, Classical Analytical SFC Column (4.6 mm i.d.), S-3 µm, 250 x 4.6 mm -
    KSC99S05-1546WTS Alcyon SFC CSP Cellulose-SC, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 150 x 4.6 mm -
    KSC99S05-15Q1WTS Alcyon SFC CSP Cellulose-SC, Narrowbore SFC Column (2.1 mm i.d.), S-5 µm, 150 x 2.1 mm -
    KSC99S05-2510WTS Alcyon SFC CSP Cellulose-SC, semi-preparative SFC column (10.0 mm i.d.), S-5 µm, 250 x 10.0 mm -
    KSC99S05-2520WTS Alcyon SFC CSP Cellulose-SC, semi-preparative SFC column (20.0 mm i.d.), S-5 µm, 250 x 20.0 mm -
    KSC99S05-2546WTS Alcyon SFC CSP Cellulose-SC, Classical Analytical SFC Column (4.6 mm i.d.), S-5 µm, 250 x 4.6 mm -
    SL12S05-1546WTS Alcyon SFC SIL (Silica), Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 150 x 4.6 mm -
    SL12S05-15Q1WTS Alcyon SFC SIL (Silica), Narrowbore SFC Column (2.1 mm i.d.), 12 nm, S-5 µm, 150 x 2.1 mm -
    SL12S05-2510WTS Alcyon SFC SIL (Silica), semi-preparative SFC column (10 mm i.d.), 12 nm, S-5 µm, 250 x 10.0 mm -
    SL12S05-2520WTS Alcyon SFC SIL (Silica), semi-preparative SFC column (20 mm i.d.), 12 nm, S-5 µm, 250 x 20.0 mm -
    SL12S05-2546WTS Alcyon SFC SIL (Silica), Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 250 x 4.6 mm -
    TA12S05-1546WTS Alcyon SFC Triart C18, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 150 x 4.6 mm -
    TA12S05-15Q1WTS Alcyon SFC Triart C18, Narrowbore SFC Column (2.1 mm i.d.), 12 nm, S-5 µm, 150 x 2.1 mm -
    TA12S05-2510WTS Alcyon SFC Triart C18, semi-preparative SFC column (10 mm i.d.), 12 nm, S-5 µm, 250 x 10.0 mm -
    TA12S05-2520WTS Alcyon SFC Triart C18, semi-preparative SFC column (20 mm i.d.), 12 nm, S-5 µm, 250 x 20.0 mm -
    TA12S05-2546WTS Alcyon SFC Triart C18, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 250 x 4.6 mm -
    TDN12S03-2546WTS Alcyon SFC Triart Diol, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-3 µm, 250 x 4.6 mm -
    TDN12S05-1546WTS Alcyon SFC Triart Diol, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 150 x 4.6 mm -
    TDN12S05-15Q1WTS Alcyon SFC Triart Diol, Narrowbore SFC Column (2.1 mm i.d.), 12 nm, S-5 µm, 150 x 2.1 mm -
    TDN12S05-2510WTS Alcyon SFC Triart Diol, semi-preparative SFC column (10 mm i.d.), 12 nm, S-5 µm, 250 x 10.0 mm -
    TDN12S05-2520WTS Alcyon SFC Triart Diol, semi-preparative SFC column (20 mm i.d.), 12 nm, S-5 µm, 250 x 20.0 mm -
    TDN12S05-2546WTS Alcyon SFC Triart Diol, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 250 x 4.6 mm -
    TPF12S05-1546WTS Alcyon SFC Triart PFP, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 150 x 4.6 mm -
    TPF12S05-15Q1WTS Alcyon SFC Triart PFP, Narrowbore SFC Column (2.1 mm i.d.), 12 nm, S-5 µm, 150 x 2.1 mm -
    TPF12S05-2510WTS Alcyon SFC Triart PFP, semi-preparative SFC column (10 mm i.d.), 12 nm, S-5 µm, 250 x 10.0 mm -
    TPF12S05-2520WTS Alcyon SFC Triart PFP, semi-preparative SFC column (20 mm i.d.), 12 nm, S-5 µm, 250 x 20.0 mm -
    TPF12S05-2546WTS Alcyon SFC Triart PFP, Classical Analytical SFC Column (4.6 mm i.d.), 12 nm, S-5 µm, 250 x 4.6 mm -
    • 2-3 days
    • 1-2 weeks
    • 3-4 weeks

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    Contact

    • Dr. Daniel Eßer
    • Product Manager
    • Analytical Chromatography
    • ph. +49 (0)2064 427-280