News Details

News Details

September 2020

by Thomas Kerkewitz

Allowed changes of your Ph. Eur. methods

 

Are you responsible for implementing monographs from the European Pharmacopoeia (Ph. Eur.) into your routine analysis?
 
Are you not quite sure which optimisations you are allowed to take to ensure the reproducibility of your results?
 
Because most pharmacopoeia methods are developed on older chromatographic material it is worthwhile to already switch in implementation to a more innovative column material for which not only support of the manufacturer is guaranteed, but also a consistent manufacturing process. For this, usually small changes in method parameters are necessary and your gain will be reproducible and robust results. Day by day, year by year, column by column.

Download our helpful overview of allowed changes to methods in the Ph. Eur. and we’re happy to provide you with a personal consultation.

Allowed changes of your Ph. Eur. methods

 

Your sensitivity boost in MicroLC

 

YMC MicroLC/NanoLC columns, especially packed with YMC-Triart stationary phases, provide you superior efficiencies for your analyses!

Now, this has been proven in an independent study using van Deemter analysis. The scientific approach included alternative fully porous particles and core-shell media, providing a profound evaluation of MicroLC/NanoLC columns. YMC-Triart C18 outperforms any other column!
 
Results for YMC MicroLC/NanoLC columns show:

  • superior resolution
  • increased separation speed
  • reduced solvent consumption
  • reduced cycle times

Check out the recently published brochure or visit our homepage to learn more about YMC’s MicroLC and NanoLC columns.
 

Highest Efficiency: Van Deemter analysis

YMC-Triart: the guarantor for reproducibility!

 

YMC-Triart (U)HPLC columns, available in eight different modifications, provide excellent reproducibility.

YMC-Triart is produced using tightly controlled particle formation technology which has been adapted from a micro-reactor process. This recently developed production process developed by YMC results in exceptionally narrow particle and pore size distributions.
These uniform particles in combination with YMC’s extensive packing experience result in an excellent reproducibility both lot-to-lot and column-to-column.

The example (see figure) demonstrates, that YMC-Triart shows superior reproducibility for basic compounds as well as for coordination compounds.

For more information about the YMC-Triart series download the YMC-Triart (U)HPLC columns catalogue!

 

 

YMC-Triart: the guarantor for reproducibility!

 

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