YMC has achieved considerable improvements in the manufacture of its classical silica base. This has given rise to an improved generation of stationary phases with superior physical attributes: YMC*Gel High Grade (HG)-series.
Due to its improved mechanical stability and its more uniform pore and particle size distribution the benefits of YMC*Gel HG-series products are:
- Higher sample load
- Less backpressure
- Longer column usage
- More repacking times possible
- More efficient column packing
Available Phases are:
[nm / Å]
|12, 20, 30 /
120, 200, 300
|Surface Area [m²/g]||330, 175, 100|
|Particle Sizes [µm]||10, 15, 20, 50|
|Pore Sizes||12, 20, 30 nm / 120, 200, 300 Å|
|Surface Area||330, 175, 100 m2/g|
|Particle Sizes||10, 15, 20, 50 µm|
The silica-based YMC*Gel Diol-HG is a rugged and efficient normal phase, reversed phase or size exclusion material. It is generally used for the separation of biomolecules and pharmaceuticals. As the non-specific adsorptive sites have been eliminated it exhibits better performance characteristics for size separations than nonbonded silica. YMC*Gel Diol-HG is available in four porosities: 6, 12, 20 and 30 nm. Diol- 12 is most suitable for the separation of peptides or oligosaccharides with molecular weights of 10,000 or less, whereas Diol-20, and -30 (either used individually or in combination) are suitable for separations of proteins and other water-soluble compounds with molecular weights of 10,000 to several hundred thousands.
Improvements in the production process of the base silica has led to particles with higher mechanical stability and more uniform particle and pore size distribution (see microscopy images below).
A narrower particle size distribution with lower tendency for the HG-silica material to produce fines translates directly into a reduced backpressure of preparative processes. On average a 7% backpressure reduction can be seen, which increases dramatically with each repacking step.
YMC*Gel is available in a variety of different pore sizes. Pore sizes are usually matched to sample molecule sizes. Pore sizes can also be used to adjust ligand density and hence retention characteristics of a bonded phase, since the size of the pores also affects the total media surface area in a packed column.
Please contact YMC for pricing or specific solutions for your purification process.
Product Manager Bulk Media
ph. +49 (0)2064 427-280
|DLG12S11||YMC*Gel Diol-HG, 12nm S10µm|
|DLG12S16||YMC*Gel Diol-HG, 12nm S15µm|
|DLG12S21||YMC*Gel Diol-HG, 12nm S20µm|
|DLG12S50||YMC*Gel Diol-HG, 12nm S50µm|
|DLG20S11||YMC*Gel Diol-HG, 20nm S10µm|
|DLG20S16||YMC*Gel Diol-HG, 20nm S15µm|
|DLG20S21||YMC*Gel Diol-HG, 20nm S20µm|
|DLG30S11||YMC*Gel Diol-HG, 30nm S10µm|
|DLG30S16||YMC*Gel Diol-HG, 30nm S15µm|
|DLG30S21||YMC*Gel Diol-HG, 30nm S20µm|