News Details

News Details

June 2020

by Thomas Kerkewitz

Technical note: Comparitive study of pressure flow characteristics of IEX resins

The pressure flow characteristics of IEX resins are mainly based on the physical properties of the base beads used for the resin. In general, the particle size of the resin is the overriding parameter responsible for the separation efficiency according to the diffusion processes and for the inherent backpressures during the chromatographic processes. In this technical note, the pressure flow characteristics of two commonly used AEX resins are compared.

The YMC resin shows much better pressure flow characteristics. As a result, the YMC resin can be used over a greater flow rate range and with higher flow rates. For a pressure range of up to 3 bar, the YMC resin can be used with flow rates of up to 800 cm/hr for a bed length of 24 cm.


Fig.: Pressure flow curves for YMC’s BioPro IEX Q75 and the reference resin for a pressure range up to 3.5 bar.


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